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Effects of hormones and growth factors on TGF-β1 expression in bovine mammary epithelial cells | Journal of Dairy Research | Cambridge Co

Effects of hormones and growth factors on TGF-β1 expression in bovine mammary epithelial cells - Volume 72 Issue 1 - Joanna Zarzyńska, Małgorzata Gajewska, ...

Research Article Protection of Bovine Mammary Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Cell Damage by Resveratr

e mammary epithelial cells (MECs) of high-producing dairy co wsarelikelytobesubjecttooxidativestress(OS)duetothe intensive cell metabolism. e objectives of this study were to investigate the cytoprotective e ects of resveratrol against hydrogen peroxide- (H 2 O 2 ...

mTORC2 Regulates Lipogenic Gene Expression through PPARγ to Control Lipid Synthesis in Bovine Mammary Epithelial Cel

In the present study, mTORC2 was inactivated by the ATP-competitive mTOR inhibitor AZD8055 or shRNA targeting RICTOR in primary bovine mammary epithelial cells (pBMECs). ...

Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS‑mediated PI3K/AKT signaling pathw

Reactive oxygen species (ROS) cause oncogenic mutations through direct interaction with DNA. Carvedilol (CAR) exhibits antioxidative activity, and pre‑clinical studies have identified that CAR may prevent malignant transformation in certain carcinogenic models.

Abstract C27: Activation of PKA induces a mesenchymal-to-epithelial transition and epigenetic reprogramming-mediated loss of tumor initiating .

Request PDF on ResearchGate | Abstract C27: Activation of PKA induces a mesenchymal-to-epithelial transition and epigenetic reprogramming-mediated loss of tumor initiating ability | Cancer stem cells (CSCs) have emerged in recent years as important targets for ...

[Frontiers in Bioscience, 4, d898-907, December 1, 1999] ANTISENSE DNA-TARGETING PROTEIN KINASE A-RIA SUBUNIT: A NOVEL APPROACH TO CANCER TREATME

Antisense DNA-targeting protein kinase A-RIA subunit 900 We compared growth and transformed properties of the PKA subunit gene infectants with parental non-infectant control cells. We used the following criteria: growth in monolayer culture, thymidine ...

Breast Cancer–Associated PIK3CA Mutations Are Oncogenic in Mammary Epithelial Cells | Cancer Resear

In addition, expression of p110α mutants in mammary epithelial cells induces multiple phenotypic alterations characteristic of breast tumor cells, ...

Mammary stem cells, self-renewal pathways, and carcinogenesis | Breast Cancer Research | Full Te

Mammary stem cells, self-renewal pathways, and carcinogenesis Suling Liu 1, Gabriela Dontu 1 & ... Differentiation and self-renewal in vivo are tested by implanting human mammary epithelial cells into the cleared mammary fat pads of immunodeficient mice ...

c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting and breast cancer gene 1 expressi

www.impactournals.comoncotarget 1 ncotarget www.impactjournals.com/oncotarget/ Oncotarget, Advance Publications 2015 c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast ...

LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF‐κB/NLRP3 inflammasome pathw

sponse of bovine mammary epithelial cells. Materials and methods: Two inflammatory bovine mammary alveolar cell‐T (MAC‐T) models were established by infecting the cells with coli) and Escherichia coli (E. ...

Glucose transporter in bovine mammary epithelial cells is an asymmetric carrier that exhibits cooperativity and trans-stimulation | American .

Glucose transport kinetics were quantified in isolated bovine mammary epithelial cells using 3-O-methyl-d-glucose. ... A carrier-mediated mechanism for pyridoxine uptake by human intestinal epithelial Caco-2 cells: regulation by a PKA-mediated pathway ...

Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic .

Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Toggle navigation Sign In Join Now Categories Authors Videos Journals Stories Login Categories ...

Epithelial–mesenchymal transition - Wikiped

When TGF-β acts on activated Ras-expressing mammary epithelial cells, EMT is favored and apoptosis is inhibited. This effect can be reversed by inducers of epithelial differentiation, ...

Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer - Sciacovelli - 2017 - The FEBS Journal - Wiley Online Libra

Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer Authors Marco Sciacovelli, ... These genes were found upregulated also upon induction of EMT by expression of Twist1 in human mammary epithelial cells. Among these enzymes was ...

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating abili

enables carcinoma cells to acquire malignancy-associated traits and properties of tumor-initiating cells ... (MET) in mesenchymal human mammary epithelial cells. Activation of PKA triggers PHF2-mediated epigenetic reprogramming of TICs This study ...

Targeting of PKA in Mammary Epithelial Cells | SpringerLi

Abstract Targeting of protein kinases, promoting association with specific partner-molecules and localisation to particular sites within the cell, has come to be recognised as a key mechanism for attributing specificity to these enzymes. In mammary epithelial cells ...

[email protected]: Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating abili

... (PKA) induce a mesenchymal-to-epithelial transition (MET) in mesenchymal human mammary epithelial cells. PKA activation triggers epigenetic reprogramming of TICs by the histone demethylase PHF2, which promotes their differentiation and loss of tumor ...

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. | PubFac

The epithelial-to-mesenchymal transition enables carcinoma cells to acquire malignancy-associated traits and the properties of tumor-initiating cells (TICs). TICs have emerged in recent years as important targets for cancer therapy, owing to their ability to drive ...

Biology of the Mammary Gland - John A Mol, Roger A Clegg - Häftad (9781475786439) | Bok

Köp Biology of the Mammary Gland av John A Mol, Roger A Clegg på Bokus.com. Gå till mobilversionen av bokus.com Lyssna fritt i 30 dagar! Ange kod: play30 Fri frakt Billiga böcker Snabba leveranser Inloggad som (logga ut) Mina sidor Varukorg Till kassan ...

MicroRNA-221 regulates proliferation of bovine mammary gland epithelial cells by targeting the STAT5a and IRS1 genes - ScienceDire

MicroRNA-221 regulates proliferation of bovine mammary gland epithelial cells by targeting the STAT5a and IRS1 genes Author links open overlay panel B.L. Jiao a X.L. Zhang a S.H. Wang a L ...